A Screening Assay For Z α1‐Antitrypsin Aggregation
نویسندگان
چکیده
منابع مشابه
Assay Interference by Aggregation
Aggregation is a common mechanism of compound-mediated assay interference encountered in high-throughput screening (HTS) and follow-up experiments. Compounds that form aggregates in situ can nonspecifically perturb biomolecules in biochemical and cell-based assays. Nonspecific bioactivity from aggregation can waste significant resources when unaccounted for in assay design and readout interpret...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.907.6